Cardiovascular Epigenetics
نویسندگان
چکیده
منابع مشابه
Advances in Genetics Cardiovascular Epigenetics
Epigenetics is the study of heritable alterations in phenotypes and gene expression that occur without changes in the DNA sequence. Epigenetic mechanisms are flexible genomic factors that not only can change genome function under exogenous influence, but also can provide a molecular substrate that allows for the stable propagation of gene expression states from one generation of cells to the ne...
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PURPOSE OF REVIEW Here, we provide a summary of the current knowledge on the impact of early life nutrition on cardiovascular diseases that have emerged from studies in humans and experimental animal models. The involvement of epigenetic mechanisms in the Developmental Origins of Health and Disease will be discussed in relation to the implications for the heart and the cardiovascular system. ...
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Genetic and epigenetic factors are of great importance in cardiovascular biology and disease. Tobacco-smoking, one of the most important cardiovascular risk factors, is itself partially determined by genetic background and is associated with altered epigenetic patterns. This could render the genetics and epigenetics of smoking-related cardiovascular disease a textbook example of environmental e...
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BACKGROUND Although it is well established that African Americans (AA) experience greater social stressors than non-Hispanic Whites (NHW), the extent to which early life adversity and cumulative social stressors such as perceived discrimination, neighborhood violence, subjective social status, and socioeconomic status contribute to disparity in coronary heart disease (CHD) and stroke between AA...
متن کاملEpigenetics
By the time the reader reaches Chapter 20, which focuses specifically on cancer, the mechanisms and symptoms of cancer are relatively easy to understand. Chapter 20 covers topics such as the cellular phenotypes of cancer, genes linked to cancer, and cancer treatment. While the primary literature citations at the end of the chapter will provide good starting points for the curious student, a mor...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Genetics
سال: 2010
ISSN: 1942-325X,1942-3268
DOI: 10.1161/circgenetics.110.958744